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global point of care

Panbio™ Dengue Early Rapid

De Panbio™ Dengue Early Rapid is een NS1-antigeenserum, plasma of volbloed immunochromatografisch assay voor dengue. Bedoeld voor de kwalitatieve detectie van NS1-antigeen in serum, plasma of volbloed gebruikt als hulpmiddel in de klinische laboratoriumdiagnose van patiënten met symptomen die overeenkomen met dengue (knokkelkoorts). De Panbio™ Dengue Early Rapid moet worden gebruikt in combinatie met andere serologische tests voor dengue.

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Dengue Early Rapid Dengue Early Rapid Dengue Early Rapid
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Voordelen
  • Het NS1-antigeen kan in serum worden gedetecteerd vanaf dag 1 na het ontstaan van koorts tot en met dag 91,2,3. Dit in vergelijking tot IgM-antistoffen die pas op dag 3-5 kunnen worden gedetecteerd4,5.
  • Het nieuwe formaat van dit hulpmiddel voor dengue-NS1-detectie presteerde beter, is gebruiksvriendelijk en gemakkelijk te interpreteren in vergelijking met het strookformaat.
Gedetailleerde informatie

Specificaties

  • Sensitiviteit: 91,89% (102/111)
  • Specificiteit: 98,39% (183/186)

PRODUCT CODES

Panbio™ Dengue Early RapidCode
Panbio™ Dengue Early Rapid01PF20 (25T/Kit)
Aanverwante producten

Referenties

  1. Libraty DH, Young PR, Pickering D, Endy TP, Kalayanarooj S, Green S, Vaugh OW, Nisalak A, Ennis FA and Rothman AL. (2002). High circulating levels of the dengue virus non-structural protein NS1 early in dengue illness correlate with the development of dengue haemorrhagic fever. J Infect Dis. 186:1165-1168.
  2. Alcon S, Talarmin A, Debruyne M, Falconar A, Deubel V,and Flammand M (2002). Enzyme-linked immunosorbent assay specific to dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections. J Clin Microbiol. 40:376-381.
  3. Young PR, Hilditch PA Bletchly C and Halloran W. (2000). An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients. J Clin Microbiol. 38:1053-1057. 
  4. Lindegren G, Vene S, Lundkvist A and Falk KI. (2005). Optimized diagnosis of acute dengue fever in Swedish travelers by a combination of reverse transcription-PCR and Immunoglobulin M detection. J Clin Microbiol. 412850-2855. 
  5. Shu P and Huang J. (2004). Current advances in dengue diagnosis. Clin Diagn Lab Immunol. 11:642-650. 
  6. Fry S, e al (2011). The Diagnostic Sensitivity of Dengue Rapid Test Assays is Significantly Enhanced by Using a Combined Antigen and Antibody Testing Approach. PLoS Negl Trop Dis 5(6y, 199. doi:10.1371/journal.pntd.0001199 

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