GLOBAL POINT OF CARE
Determine™ Hiv-1/2 Ag/Ab Combo
It’s Time To Resume Regular Testing With The Right Test
Determine™ Hiv-1/2 Ag/Ab Combo
It’s Time To Resume Regular Testing With The Right Test
Determine™ Hiv-1/2 Ag/Ab Combo
It’s Time To Resume Regular Testing With The Right Test
EFFECTS OF COVID-19 ON HIV TESTING
During the pandemic, HIV testing rates decreased nationally and test sites are still working to get back to pre-pandemic rates. Now is the time to re-evaluate the HIV testing protocols, including which rapid HIV test your facility is using. Determine HIV-1/2 Ag/Ab Combo is the first and only antigen/antibody rapid point-of-care test that detects both HIV-1/2 antibodies and p24 antigen – enabling early detection to link individuals to care sooner and avoid further transmission.
Rapid And Early Identification Of Hiv Infections
Abbott’s Determine HIV-1/2 Ag/Ab Combo Test is the only FDA cleared, CLIA waived, rapid point-of-care test that detects both p24 antigen and antibodies on single test strip.
Using an antigen and antibody test allows detection of both acute and chronic HIV infections – detecting HIV infections sooner (acute phase) than antibody-only tests.1 Individuals in the acute phase are 26X more contagious than those in the chronic phase so knowing their status would help to lower transmission rates.4
Detecting HIV Sooner than conventional antibody-only tests1-3
POC = point of care | RNA = ribonucleic acid
*Not comparable to molecular testing.
EASY-TO-USE POINT-OF CARE SCREENING
Performed in 3 easy steps with minimal training to allow testing across a range of test sites
99.9% overall clinical sensitivity for all sample types - capillary and venous whole blood, serum, and plasma
Results in just 20 minutes
Test in Three Easy Steps
1. Prepare Test
Bend along the perforation, then tear one strip from the right and remove cover.
2. ADD SELECTED SAMPLE
Fingerstick Whole Blood
Apply 50 μL of sample by touching the tip of the capillary tube to the sample pad. Wait 1 minute, then add chase buffer.
Venous Whole Blood
Apply 50 μL of sample by touching the tip of the precision pipette to the sample pad. Wait 1 minute, then add chase buffer.
Serum or Plasma
Apply 50 μL of sample by touching the tip of the precision pipette to the sample pad.
3. Read Results
Read the results for both the free HIV-1 p24 antigen (Ag) and HIV-1/2 antibodies (Ab) in just 20 minutes.
Please refer to the full instructions prior to running this test. Full instructions for the Determine™ HIV-1/2 Ag/Ab Combo test can be found in the package insert.
references
- Masciotra, S, et al. Performance of the Alere Determine™ HIV-1/2 Ag/Ab Combo Rapid Test with specimens from HIV-1 seroconverters from the US and HIV-2 infected individuals from Ivory Coast. J Clin Virol 2013: Published online 05 August 2013. DOI: 10.1016/j.jcv.2013.07.002 http://www.journalofclinicalvirology.com/article/S1386-6532(13)00277-1/abstract
- Fiebig EW, Wright DJ, Rawal BD, et al. Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS. 2003;17(13):1871-79.
- Patel P, Mackellar D, Simmons P, et al. Detecting acute human immunodeficiency virus infection using aRNA, 2006-2008. Arch Intern Med. 2010;170(1):66-74.
- Miller WC, Rosenberg NE, Rutstein SE et al. Curr Opin HIV AIDS. 2010;5(4): 277–282. doi:10.1097/COH.0b013e32833a0d3a.
