Global Point of Care
Abbott Point of Care (APOC) partners with physicians and researchers globally to advance scientific knowledge and evidence of our products in various clinical settings to help accelerate patient care. Below is a compilation of peer reviewed journal articles and editorials demonstrating the clinical, analytical, operational, and economic value of APOC products.
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Title |
Source |
Sample size |
Summary |
|---|---|---|---|
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ACADEMIC EMERGENCY MEDICINE. Bazarian et al 2021; 00:1–10 |
2011 |
Objectives: To determine the accuracy of a new, rapid blood test combining measurements of both glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) for predicting acute traumatic intracranial injury (TII) on head CT scan after mild traumatic brain injury (mTBI). Findings: i-STAT TBI Plasma test had high sensitivity for prediction of acute TII, comparable to lab-based platforms. The speed, portability, and high accuracy of this test may facilitate clinical adoption of brain biomarker testing as an aid to head CT decision making in EDs. |
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ADVANCED EMERGENCY NURSING JOURNAL, |
201 |
Objectives: Impact of point of care (POC) troponin testing on turnaround times, door-to-troponin result time, ED Length of Stay (LOS) in patients with chest pain, and staff satisfaction with POC testing was evaluated. |
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Title |
Source |
Sample size |
Summary |
|---|---|---|---|
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Clinical Evaluation of Measuring the ACT During Elective Cardiac Surgery with Two Different Devices |
JOURNAL OF EXTRA CORPOREAL TECHNOLOGY, |
402 |
Objectives: Multi-site study across UK, South Africa and Switzerland evaluated Activated Clotting Time (ACT) measurements with two devices, i-STAT and Hemochron Jr. Patients undergoing elective cardiac surgery on cardiopulmonary bypass were included. Findings: i-STAT ACT test demonstrated good correlation with Hemochron Jr with i-STAT reading slightly higher than Hemochron Jr. Additionally, i-STAT consistently demonstrated lower within-subject coefficient of variation (WSCV) compared to Hemochron Jr, making it more reliable for clinical decision making. Authors commented that the better reliability of the i-STAT may be due to the difference in ACT methodology. |
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A Two Site Comparison of Two Point of Care Activated Clotting Time Systems |
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, |
177 |
Objectives: i-STAT Activated Clotting Time (ACT) and Hemochron Signature Elite ACT values were compared using split samples from patients undergoing invasive surgery at two cardiothoracic institutes in the Netherlands and Germany. Findings: i-STAT ACT values demonstrated better reproducibility (mean difference - 4.3% vs. 9.1%) and correlation compared to the Hemochron. In the therapeutic area (>250 s), Hemochron duplicate measurements became less precise. There are different possible explanations for the correlation results between the Hemochron and the i-STAT. The i-STAT is less susceptible to changes in fibrinogen levels, temperature, hematocrit and hemodilution compared to the Hemochron. These findings reflects precision and not accuracy. Since there is no true ACT value, clinicians rely on the precision (reproducibility) of tests. |
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Title |
Source |
Sample size |
Summary |
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CLINICO ECONOMICS AND OUTCOME RESEARCH, |
200 |
Objectives: Economic value of i-STAT point-of-care (POCT) testing at six primary health care facilities in rural and remote communities in Australia, where hospital and laboratory facilities are unavailable were evaluated. Economic evaluation was conducted using data from patients presenting with three common acute conditions (chest pain, chronic renal failure due to missed dialysis session(s), and acute diarrhea). The number of unnecessary medical evacuations prevented with the use of POCT as an aid in decision-making for acutely ill patients was used as a basis of calculating cost savings per patient and Northern Territory (NT) wide. |
The results shown here are specific to one health care facility and may differ from those achieved by other institutions.
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