Elevated Bone resorption is the primary cause of age related bone loss and low bone mass often results in osteopenia and is the major cause of osteoporosis. Osteomark® NTx measures the cross-linked N-telopeptides of bone type I collagen (NTx). The NTx molecule’s unique amino acid sequence and orientation of the cross-linked alpha-2 (I) N telopeptide is specific to bone. Therefore measuring the levels of NTx helps in monotoring the primary cause of age related bone loss that leads to Osteoporosis.